The Do-Si-Do high hits you fast and hard with a cerebral rush of euphoric energy that lasts for only a few moments before fading into a happy stoney introspection. As your mind falls deeper and deeper into itself, a warming body buzz will start to wash over you, first moving down your spine before extending through your limbs, leaving you helplessly sedated and completely couch-locked. With these hard-hitting effects, Do-Si-Do is said to be perfect for the experienced user suffering from conditions such as insomnia, chronic pain, nausea, and depression.